Name | Description | Invasive / Non-invasive / Semi-invasive | Techs Used | Tech used (specifics) | Funding | Year Founded | Link | Associated Labs/Orgs | New/Existing Tech |
---|---|---|---|---|---|---|---|---|---|
Stem cells grown in electrode grids, grafted onto cranial nerves. | Invasive | Electrodes | Neural stem cells, grown on chips and grafted into neural tissue. Starting with retinal implants | $47.3M | 2021 | New | |||
Patented minimally invasive brain implants in order to replace, restore, and eventually augment lost or impaired neurological function. | Invasive | ElectrodesNeurostimulationeCOG | Novel neural interface using μECoG and comprising conformable thin-film electrode arrays and a minimally invasive surgical delivery system | $12M | 2020 | Many people in team ex-Neuralink. CEO is director of Sinai Biodesign Incubator. | New | ||
Developing an implantable neural interface for frontier neuroscience research and ambitious future applications; Chinese company aiming to rival Neuralink. Working on both software and hardware. Bidirectional BCI chip already created. | Invasive | Electrodes | BMI including implants which send info to and receive info from neurons | $15.6M | 2019 | Incubated in Tsinghua University | |||
Graphene-based bioelectrical implants which promise miniaturization and signal resolution greater than metal-based interfaces. | Invasive | ElectrodesAI | Graphene electrodes | $16.9M | 2019 | Catalan Institute of Nanoscience & Nanotechnology; National Graphene Institute at University of Manchester; Graphene Flagship Project; INNERVIA Bioelectronics (subsidiary) | New | ||
Creating an artificial retina using patented electronic neuron for patients with damaged photoreceptors; later plans to expand use of neuron to address other conditions in other areas of the body. | Invasive | CMOS | Implanted, analog electronic CMOS circuit that detects and produces biomimetic spikes | $1.3M | 2019 | CNRS (French National Center for Scientific Research); SPINE, Lille University | New | ||
Carbon-based implantable devices which minimise biological degredation and read both electrical and chemical signals; integrated on-chip self-powering energy sources. | Invasive | DBSeCOGNeurotransmitter | Carbon-based electrodes | 2017 | NanoFAB.SDSU; Center for Neurotechnology | New | |||
So-called “neural dust” platform - tiny, battery-free, wireless implanatable devices developed at UC Berkeley which use ultrasound. They can gather precise data and stimulate nerves. Acquired by Astellas. https://iota.bio/astellas-to-acquire-iota-biosciences | Invasive | CMOSNeurostimulationNeurotransmitterUltrasound | Neural Dust - piezoelectrical crystals and CMOS powered by ultrasound | $15M | 2017 | Maharbiz Group, UC Berkeley | New | ||
Endovascular BCI; electronics surgically delivered to the wall of blood vessels to give access to unprecedented data. First device, the Stentrode, is placed in a motor cortex vein and has enabled patients with paralysis to perform daily tasks without movement in human trials. | Invasive | EEGNeurostimulationNeuroprosthetics | Implanted chip used for “Neuro EP” - Neurointerventional Electrophysiology | $50M | 2016 | Vascular Bionics Laboratory, University of Melbourne; funded by DARPA and DoD | New | ||
Micron-scale threads with many electrodes that are connected to a neural implant, “The Link”, to enable human-machine symbiosis. Aiming to build devices with at least two orders of magnitude more electrodes than current approved devices. | Invasive | LFPElectrodesNeurostimulation | Novel flexible electrodes + surgical robot to implant them precisely and reliably | $363M | 2016 | New | |||
Treating rheumatoid arthritis by stimulating the splenic nerve with an implant; later expanding to address other conditions. | Invasive | Neurostimulation | Implantable components inserted via laparoscopy; accompanying software for both user and clinician | 2016 | Partnership between GSK and Verily Life Sciences | ||||
Microscale robots to deliver biologics or small molecule therapies locally to targeted disease areas to help patients suffering from severe brain disorders. | Invasive | Microrobotics | Injected, remote-controlled microbot | $20M | 2016 | Micro, Nano, and Molecular Systems Group, Max Planck Institute for Intelligent Systems | New | ||
Proprietary neural interface and AI platform to measure data in real time; development of a “code” for the nervous system to better understand disease and develop treatments; | Invasive & Non-invasive | AINeurofeedbackNeuromodulation | AI-powered neural interfaces | $5.7M | 2015 | ||||
BCI system comprised of biocomptabile microelectrodes arrays combined with cortical modules to convert neural signals into data; a cranial hub and transceiver to power the system and relay information. Initial use focusses on translating neural data into text or synthesized speech. | Invasive | Electrodes | Cortex - implantable brain-computer interfaces using microelectrode arrays | $49.4M | 2015 | Massachusetts General Hospital’s (MGH) Center for Neurotechnology and Neurorecovery | |||
Medical devices using peripheral nerve stimulation (PNS) for pain management/relief. FDA-approved “SPRINT” PNS system. | Invasive | Neurostimulation | Selectively stimulating targeted peripheral nerve fibers with percutaenous PNS | $104M | 2010 | Grill Lab, Duke University | |||
DBS for Parkinson's through an electrode which can direct the stimulus to highly specific and selectable areas of the brain. | Invasive | DBS | MEMS-based DBS using 12 electrode lead for directional stimulation | $65.3M | 2008 | Swiss Federal Institute of Technology in Lausanne; Microsystems Laboratory of Prof. Philippe Renaud | |||
Invasive brain-computer interfaces, restoring function in patients suffering from neurological disease. FDA-cleared configuration called the NeuroPort Array; planned innovations include new surgical solutions, flexible materials, depth electrodes, additional channel count, and enhanced AI — just received a 2021 Breakthrough Designation from the FDA. | Invasive | ElectrodesAIeCOG | Implantable chip for BCI; neural interfaces (electrodes), biocompatible materials and implantable electronics, with a focus on system integration and miniaturization. | $10M | 2008 | Churchland Lab, Columbia University; tech used in over 700 labs worldwide | |||
Combines Vagus Nerve Stimulation (VNS) and therapy, improving quality of life for patients with chronic neurological conditions. FDA-approved “Vivistim” system to restore arm + hand motor function after strokes; “Serenity” system being studied for application to tinnitus. | Invasive | VNS | Vagus Nerve Stimulation (VNS) paired with: sounds to suppress tinnitus; limb rehabilitation therapy to restore motor function after stroke. | $42.1M | 2007 | ||||
Working towards a BMI which uses soft, scalable and stable next generation neural probes with subcellular resolution and ultra-high bandwidth; solving the mechanical mismatch between brain tissues and electronic materials. | Invasive | ElectrodesNeurostimulation | Soft implants for BMIs | $1M | 2021 | Jia Liu Group, Harvard University | New | ||
KIWI (Kinetic Intelligent Wireless Implant): small, wireless implant for DBS, recording brain activity and delivering electrical and optical signals to target areas, with algorithms that will determine the therapeutic response; improved by ML. Also creating internally-developed surgical procedure and cloud-based software platform for the data. | Invasive | DBSEEGAINeurofeedback | Wireless DBS implant with carbon nanotube connectors; algorithms to determine therapeutic response. | $1.3M | 2017 | Computational Neuroscience Lab, Oxford University; Oxford Centre for Functional Neurosurgery | |||
Device containing genetically engineered cells encased in an immune-shielding capsule that can continuously produce therapeutic levels of biotherapeutics after implantation in brain for neurodegerative diseases. Company potentially no longer active. | Invasive | Neurotransmitter | Neurotrophic proteins, bioreactors | 2017 | Brown University | ||||
Skull-mounted brain pacemaker to increase cerebral blood flow and therefore treat cerebrovascular diseases. Used for DBS but bypasses the need for implants in chest and neck. | Invasive | DBSLFPElectrodesNeurostimulation | Wirelessly-charged brain “pacemaker” for DBS; includes LFP recording | $2M | 2002 | Bristol Functional Neurosurgery Team; Institute of Biomedical Engineering, Oxford University | |||
[Acquired] Research hardware for calcium imaging and optogenetics (mostly for mice) | Invasive | OptogeneticsEEGEMGLFP | Neurotech hardware | 2005 | |||||
An implanted ultrasound device that increases chemotherapy drug permeability by destroying blood vessels in a localized area (around a tumor) | Invasive | Ultrasound | Low intensity pulsed ultrasound (LIPU) to disrupt blood-brain barrier (BBB) | $35M | 2010 | AP-HP, Greater Paris University Hospitals | |||
Research consortium developing and testing practical, groundbreaking medical devices. Main tech is microelectrode array for BCI. | Invasive | LFPNeuroprostheticsElectrodes | Microelectrode arrays for BCI | 2001 | Robert J. & Nancy D. Carney Institute for Brain Science, Brown University; Stibel Dennett Consortium for Brain and Cognitive Science, Tufts University; https://www.braingate.org/our-team/affiliated-institutions-supporters/ | ||||
Neurotechnology company creating the first FDA-approved "Digital Pill," a brain-computer interface (BCI) with a focus to alleviate cognitive disorders, starting with depression. Device rebalances brain networks with individualized microstimulations. | Invasive | Neurostimulation | Minimally-invasive “pill” implant for BCI | $10M | 2019 | Leuthardt Lab, Washington University St. Louis | |||
Wearable device with neural interfaces for everyday personal assistants and communication. | Non-invasive | AIEMG | Neural interfaces which translate deliberate intentions/small muscle movements into virtual interactions | $4.6M | 2021 | Stanford University | |||
Haptic recording device on the tongue for the physically impaired to interact with computers; health tracking. | Non-invasive | EEG | Haptics | $1.2M | 2019 | MIT | |||
Restoring motor function through a “neural bypass” which turn intentions into actions; signals from an intracortical implant are decoded by ML and then used to stimulate the arm by an electrode device wrapped around it. | Invasive & Non-invasive | NeurostimulationAINeuroprostheticsElectrodes | Machine-learning algorithms to decode neuronal activity and control muscle activation through a high-resolution neuromuscular electrical stimulation system | $1M | 2019 | Feinstein Institutes for Medical Research; Barrow Neurological Institute | |||
Wearable, non-invasive headband to act as a BCI, enabling new everyday virtual interactions; ultimate aim of telepathic communication. | Non-invasive | EEGVirtual Reality | $8M | 2019 | UCL; YC | ||||
Stealth working on non-invasive and minimally-invasive neuromodulation | Invasive | Neuromodulation | Potentially TMS and tDCS | 2019 | Laboratory for Cognition and Neural Stimulation, UPenn; Cognitive Neuroengineering & Wellbeing Laboratory, Drexel University | ||||
Non-invasive EEG wearable brain interface called “Crown” which delivers real-time feedback on your focus/productivity through an app and plays “productivity-enhancing” music. | Non-invasive | EEGNeurofeedback | Interface sensors detect gamma waves as proxy for focus | 2018 | |||||
Room-temperature magnetometers in a wearable device to measure brain activity for non-invasive brain interfacing. | Non-invasive | EEG | Magnetometer based on acoustically-driven ferromagnetic resonance to detect high-quality magnetic signals from neurons firing in the brain | $10M | 2018 | Salahuddin Group, UC Berkeley; Berkeley Startup Cluster | |||
Somnee device - headband which provides personalised non-invasive electrical stimulation to aid sleep; app to see data. | Non-invasive | EEGNeurostimulation | tES - Transcranial Electrical Stimulation | $6M | 2017 | CognAc lab, UC Berkeley; Center for Human Sleep Science, UC Berkeley; Knight Cognitive Neuroscience Lab, UC Berkeley | |||
First product aids getting to sleep and sleep quality by playing acoustic sound through bone conduction which is attuned to brainwaves read in real-time. Later goals: “app store” for brain states. | Non-invasive | EEGtDCS | Acoustic sound attuned to brainwaves detected from EEG | 2019 | Synthetic Neurobiology Group (Ed Boyden), MIT; Brain Computer Interface Lab and Read Group, University of Connecticut | ||||
[Acquired] A non-invasive BCI, the NextMind Sensor uses EEG technology to detect neural activity from the visual cortex. Machine learning algorithms translate them into digital commands in real time. | Non-invasive | EEGAIVirtual Reality | EEG to detect neural activity in visual cortex; ML to translate into digital commands. | $4.6M | 2017 | Brain and Consciousness Lab, École Normale Supérieure; CNRS | |||
Device to monitor moment-to-moment brain function and deliver individualized stimulation of temporal lobe to improve memory performance; first tech: Smart Neurostimulation System (SNS) intended for the treatment of memory loss after traumatic brain injury. | Non-invasive | EEGElectrodesNeurostimulationAI | Personalized stimulation therapy delivered by electrodes, cranial implant, wearable earpiece, and the Nia Cloud software platform. | $6.4M $24M from DARPA | 2016 | DARPA RAM (Restoring Active Memory) project at UPenn; Denison Group, Oxford University; Creative Destruction Lab accelerator, University of Toronto | |||
Wearable wrist device which delivers vibrations to help your body recover from stress, feel calm, and sleep better. | Non-invasive | TVS | Tuned Vibroacoustic Stimulation (TVS) | $21.4M | 2017 | University of Pittsburgh Program in Cognitive Affective Neuroscience (PICAN) laboratory | |||
Non-invasive medical device with personalisaed sensory stimulation (combining auditory stimulation with visual stimulation) which treats neurodegenerative diseases like Alzheimer’s | Non-invasive | NeuromodulationNeurostimulationElectrodes | Stimulation evokes gamma oscillations in brain, improving synaptic connections and reducing atrophy. | 2016 | Synthetic Neurobiology Group, MIT | ||||
[Acquired] Brain stimulation headseat using tDCS to treat depression, along with a behavioural therapy app. | Non-invasive | tDCS | tDCS on Dorsolateral Prefrontal Cortex | $12.6M | 2016 | ||||
Broad drug discovery platform solving the technical hurdles to assaying, analyzing, and targeting fleeting neurotoxic oligomers, enabling the central molecular cause of neurodegeneration to be addressed directly. | Non-invasive | Network-centric paradigm for drug discovery allows us to see the oligomer protein production pathway and discover small molecules that can block their generation with precision. | $40.3M | 2016 | Cambridge Centre for Protein Misfolding Diseases, University of Cambridge, Lund University | ||||
Augmented Reality tests on the patient's phone to scan for digital biomarkers of neurological diseases. Targeting Alzheimer's Disease. | Non-invasive | AI | Augmented Reality via smartphone | $24.7M | 2016 | Global Brain Health Institute | |||
Low frequency and intensity magnetic fields to promote neurological recovery; tailored therapies according to each condition having used ML algorithms on electrophysiology data. | Non-invasive | ELF/EMFAI | Electromagnetic fields (ELF-EMF) | $48.8M | 2016 | Shohami Lab, University of Jerusalem | |||
Peripheral neural interfaces based on EMG. Also AR/VR devices, experiences, and research. | Non-invasive | EMG | EMG | 2016 | |||||
Aims to make an accessible, everyday BCI; curren tproduct is “Enten”, using EEG to track focus levels and play music in the form factor of headphones. | Non-invasive | EEG | Headphones with 20 electrodes around ear pads to record EEG | $9.3M | 2015 | Direct-Brain Interface Laboratory (UM-DBI), University of Michigan | |||
Patented neural interface technology called “Neuos” - software measuring brain activity (via a third-party headset) in real-time which developers can use to make their apps more intelligent. | Non-invasive | AI | Software to process brain activity | $5M | 2016 | ||||
TES devices and certifications for dedicated healthcare providers; includes PlatoWork tDCS headset and PlatoApp to view data and link client and clinician. Commonly used to treat depression and addiction. | Non-invasive | tDCSNeuromodulationElectrodes | 3 fixed electrodes on a tDCS headset | $81.9k | 2015 | Sack Lab, Maastricht University | |||
Technology which can be used to detect early signs of cognitive impairment, especially dementia, through EEG signals collected from VR-integrated wearable sensors; headset called “LUCY”. Founded in South Korea. | Non-invasive | EEGVirtual RealityAI | VR-based cognitive assessment, analysing attention, working memory, and spatial navigation; alpha wave detection by EEG sensor. | $4.9M | 2015 | ||||
Software for virtual biopsies using Magnetic Resonance Spectroscopy (MRS), measuring concentrations of chemicals in the brain on an MRI scanner. Allows diagnosis of brain disorders. | Non-invasive | MRSMRI | Cloud software platform for MRS technology using MRI | $1.9M | 2015 | Brigham and Women’s Hosptial; Massachusetts General Hospital | |||
Offers a number of arm prostheses, both mechanical and bioelectric, cosmetic and functional, and according to different levels of amputation. | Non-invasive | EMG | Bioelectric prostheses are controlled by EMG signals read when muscles contract. Information transmitted to a wrist microprocessor. | $5.6M | 2015 | Medical Center of the Far Eastern Federal University; Vladimir Zelman Center for Neurobiology and NeuroRehabilitation at the Skolkovo Science and Technology Institute | |||
Upper limb prosthetics powered by BMI; system captures the unique EMG signals from each user and assigns them dynamically to the correct gesture using AI. | Non-invasive | EMGAI | Prosthetic hand leverages advanced BMI technology; algorithm employed that allows the hand and user to learn from each other and becomes more lifelike with each use. | $50k | 2015 | Harvard Innovation Lab | |||
BrainCo strives to apply brain machine interface (BMI) and neurofeedback training to optimize the potential of the human brain. | Non-invasive | EEG | $6M | 2015 | |||||
Brain Health App | Non-invasive | computerized cognitive test | $24.7M | 2015 | |||||
CTRL-labs is a startup pioneering the development of non-invasive neural interfaces that reimagine how humans and machines collaborate. | Non-invasive | EMG | EMG wrist wearable for VR | $67M | 2015 | ||||
Low intensity focused ultrasound | Non-invasive | low intensity focused ultrasound pulsation | $5.3M | 2015 | |||||
Winterlight has developed a tablet-based assessment that is fast, objective, and stress-free | Non-invasive | uses speech patterns to detect early signs of brain disorders | $5.2M | 2015 | |||||
Cala Health is a medical technology company pioneering a new class of electrical medicine called neuroperipheral therapy. | Non-invasive | electrical stimulation to nerves in the wrist | $148.3M | 2014 | |||||
Merging sleep science & deep-tech | Non-invasive | EEG | $57M | 2014 | |||||
Weight loss. Ssends a safe electrical pulse into the vestibular nerve. | Non-invasive | Safe electrical pulse into the vestibular nerve | $1.6M | 2014 | |||||
Continuous remote EEG, EMG and PSG for diagnostics and clinical trials | Non-invasive | EEG | $94.2M | 2014 | |||||
Sense is developing non-invasive technology. Brain scanners that will assess and monitor the neurological status of a patient in real time. | Non-invasive | radiofrequency (RF) sensor | $7.4M | 2014 | |||||
Focused on making EEG widely accessible, more efficient, and more cost-effective to improve the diagnosis and treatment of patients | Non-invasive | EEG | $121M | 2014 | |||||
AMX0035 is an investigational therapy—an oral coformulation of 2 active compounds, sodium phenylbutyrate and taurursodiol. Amylyx is currently exploring the potential of AMX0035 as a treatment option for amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, and Wolfram syndrome. | Non-invasive | Pharmaceutical | $202.2M | 2014 | |||||
Advancing research and applications of tDCS technology for cognitive performance | Non-invasive | tDCS | $24.7M | 2013 | |||||
Prosthetic arm that is mimics the movements of a real arm | Non-invasive | Prosthetic | $20.6M | 2013 | |||||
Build upon and create sound science, cutting-edge technologies and natural interfaces for accessing the world in new ways. | Non-invasive | EEG | $14.8M | 2013 | |||||
Neurotrack develops digital cognitive health solutions that enable people to assess, monitor, and strengthen their brain health to reduce the risk | Non-invasive | $50.4M | 2012 | ||||||
Creating the universal platform for brain recovery and learning ... Combining our pioneering digital therapeutics, with state-of-the-art motion analytics, cloud ... | Non-invasive | Virtual Reality | $340.7M | 2012 | |||||
Q30 Innovations' mission is to help protect the brain from the effects of head impacts on the sports field and the battlefield. | Non-invasive | Q-Collar: clamping down on blood vessels in the neck, which increases blood volume in the skull | $12.3M | 2012 | |||||
Brain Injury Monitor | Non-invasive | eye-tracking | $13.4M | 2012 | |||||
Privately held bio-informatics and technology company developing and manufacturing wearable electroencephalography products including neuroheadsets, software development kits, software, mobile apps, and data products | Non-invasive | EEG | $120k | 2011 | |||||
Quantifying the brain using optical and magnetic non-invasive interfaces | Non-invasive | FNIRS | Flow: IR Flux: OP-MEG | $107M | 2011 | New | |||
Devices usable by everyone that improve brain function via electricity, the natural language of the brain. | Non-invasive | tDCS | $13M | 2011 | |||||
Inscopix is pioneering a new paradigm in the quest to understand the brain and its diseases. Combining revolutionary technology and methods for the imaging of large-scale neural activity in a naturally behaving subject, Inscopix has developed the enabling means to relate causal neural circuit dynamics to corresponding behavior. | Non-invasive | $10M | 2010 | ||||||
EEG brain sensing devices and software solutions for real-world human behaviour research, health and neurotechnology development. | Non-invasive | EEG | $1.7M | 2010 | |||||
Blackrock Neurotech provides innovative tools and neurotech expertise to translate technology into novel, implantable clinical solutions that improve human lives. Blackrock’s precision electrode technology is at the core of many worldwide Brain-Computer Interface (BCI) innovations. Our technology has enabled BCI Pioneers to walk, talk, see, hear, and feel again. | Non-invasive | EEG | Implantables | $10M | 2008 | ||||
Created the EYE-SYNC the first and only complete platform for assessment, recovery, and management of brain injuries | Non-invasive | Virtual Reality | mobile, virtual reality-based eye tracking platform | $3.6M | 2008 | ||||
Neuroprosthesis. “Neurolutions seeks to develop a revolutionary platform of devices, based on Brain Computer Interface (BCI) technology, which promise to restore function to patients who are disabled as a result of neurological injury.” | Non-invasive | EEG | Wireless EEG electrode device | $1.3M | 2007 | ||||
“InteraXon is the maker of brainwave-controlled computing technology and applications. They have created a hardware and software platform technology that converts brainwaves into digital signals that are fed into a computer. InteraXon then provides consumers with applications that use these brainwaves to perform activities such as meditation,gaming, ADHD assistance, and many others to come.” | Non-invasive | EEG | bra | $30.4M | 2007 | ||||
“SetPoint Medical is dedicated to treating patients with debilitating inflammatory diseases, such as Crohn's Disease and rheumatoid arthritis, using proprietary implantable bioelectronic devices. The company developing novel bioelectronic medicine therapies to treat those who suffer from autoimmune diseases such as rheumatoid arthritis,Crohn's Disease, and multiple sclerosis.” | Non-invasive | Electrodes | implant provides direct electrical stimulation of the vagus nerve | $251.4M | 2006 | ||||
"electroCore, Inc. is a commercial stage bioelectronic medicine company dedicated to improving patient outcomes through its platform non-invasive vagus nerve stimulation therapy initially focused on the treatment of multiple conditions in neurology. The company’s current indications are for the preventative treatment of cluster headache and migraineand acute treatment of migraine and episodic cluster headache.” | Non-invasive | Electrodes | vagus nerve stimulation (nVNS) - emits an electrical pulse | $145.5M | 2005 | ||||
“Neuronetics is focused on developing non-invasive therapies for psychiatric and neurological disorders using MRI-strength magnetic field pulses. They are the first and only company to have a non-systemic and non-invasive depression treatment cleared by the FDA for patients who have not benefited from prior antidepressant treatment.” | Non-invasive | TMS | TMS (transcranial magnetic stimulation) | $313.4M | 2003 | ||||
"FocusCalm is a brain-machine interface company, incubated in the Harvard Innovation Lab, dedicated to improving lives through wearable technology/neuroscience” | Non-invasive | EEG | 0 | ||||||
NeoRhythm PEMF therapy devices emit clinically and scientifically proven frequencies | Non-invasive | PEMF | 0 | ||||||
Augmented reality & gaming experiences powered by non-invasive BCI, development of new hardware including FNIRS | Non-invasive | ECG | 0 | ||||||
Brain training program using neurofeedback from EEG | Non-invasive | EEG | 0 | ||||||
EEG hardware, high quality consumer grade 16 channel dry electrodes | Non-invasive | EEG | 0 | ||||||
Wearable patch to predict epileptic seizures before happening and ultimately combine with neurostimulation to prevent seizures. | Non-invasive | Neurostimulation | 0 | ||||||
An EEG+VR startup that designs empathy and positivity themed games and experiences for the terminally ill and mentally ill | Non-invasive | EEG | $250k | 0 | |||||
EEG + CV company that can suggest interesting regions in images and reconstruct images from EEG recordings | Non-invasive | EEG | 0 | ||||||
Making gaming hardware | Non-invasive | ECG | 0 | ||||||
An SDK for BCI's, for unity, swift, java, etc | Non-invasive | $1.2M | 0 | ||||||
tCDS therapy based in Korea designed for treating depression (also does consumer EEG) | Non-invasive | EEG | $4M | 0 | |||||
Measures fluid asymmetry betweeen cerebral hemispheres | Non-invasive | EEG | $8M | 0 | |||||
EEG consulting for applications like marketing, gaming, etc | Non-invasive | EEG | $17M | 0 | |||||
Neuroscience consulting services; apply EEG and run analytics for studies, commercial applications | Non-invasive | EEG | $18M | 0 | |||||
Medical device EEG designed for diagnosing specific areas of the brain damaged after stroke. The application layer for medical EEG for sleep studies and epilepsy | Non-invasive | EEG | $872M | 0 | |||||
“OccamzRazor combines machine learning and first-in-class biological techniques to improve outcomes in drug discovery and development. Our analysis pipeline consists of two proprietary technologies, Panoramic AI and RazorBrain. Together, they are designed to extract data from unstructured text sources (publications, patient reported outcomes, etc.)and join them with structured data (genomics, proteomics, phenomics, etc.) to generate stronger drug discovery hypotheses and more valuable insights. Successful applications include data extraction and curation from biomedical text, novel target identification, and drug repurposing/repositioning.” | Non-invasive | Panoramic AI and RazorBrain. | $12.4M | 0 | |||||
PureTech Health is a biotechnology company which develops medicines to combat serious diseases. | Non-invasive | $105M | 0 | ||||||
Develops a non-invasive neural input technology that allows operation and control of digital devices using subtle finger movements and fingertip pressure. | Non-invasive | neural input technology | $3.5M | 0 | |||||
Aiming single-shot treatment for depression based on genome, phenome, network connectivity, metabolome, microbiome, reward processing, plasticity levels, HPA axis function | Non-invasive | single-shot treatment | $300M DARPA | 0 | |||||
The NeuroPace RNS System is the only FDA-approved epilepsy device that delivers personalized treatment by responding to abnormal brain activity and provides | Invasive & Non-invasive | DBS | Epilepsy device | $247.3M | 1997 | ||||
Mindstate Design Labs is a preclinical-stage biotechnology company developing the next generation of psychedelic-inspired therapeutics for intractable mental health conditions. | Biotech - psychedelic-inspired therapeutics | $11.6M | 2021 | ||||||
E11 Bio builds new technology for full-stack brain architecture mapping. It enables new treatments for brain disorders, new experimental paradigms, and provides foundational technology for brain mapping. | full-stack brain architecture mapping | 2021 | |||||||
Beacon’s EEG neurobiomarker platform is engineered to accelerate clinical trials and enable new treatments for patients with neurological and psychiatric disease. | EEG | $27M | 2019 | ||||||
Neurostimulator for Alzheimer’s patients | 2017 | ||||||||
Brain-inspired analog-based circuits | artificial intelligence processors | $32M | 2017 | ||||||
Combining neurotechnology, augmented reality and artificial intelligence to create a "look-and-think” interface for next-generation spatial computing applications. | $1.9M | 2017 | |||||||
Cerebral organoids for drug discovery | $46M | 2017 | |||||||
Brain stimulation for memory loss | DBS | precision DBS | $6.4M | 2016 | |||||
“Koniku is a synthetic biotechnology company. We leverage synthetic biology merged with silicon to build devices to map all volatile organic compounds that touch human life. Our smell cyborgs are capable of autonomously and intelligently reading the air. We engineer proteins in biological neurons to create precise protein particle interactions. The biological cells function as sensors, amplifiers and biological signal processors.” | silicon-based devices | $1.7M | 2015 | ||||||
Research company dedicated to advancing the science of memory. | $120k | 2015 | |||||||
Next-generation medicines from human genomics · Our focus is patients. · We begin from day one with patient data. | uses patient genomes, gene expression, and epigenomics to identify new therapeutic gene targets, predict effective drugs, and stratify patient subpopulations for increased clinical success. | $134.1M | 2015 | ||||||
Digital Phenotyping. AI-powered neural interfaces. Runs in the background on your phone and tracks how you touch the phone while using it | $160M | 2014 | |||||||
Developing a therapy combining a spinal cord implant with gravity-assisted training | 2014 | ||||||||
Onward is developing an Implantable Neuro-stimulation System (INS) with real-time motion feedback and uses training tools to rehabilitate patients suffering from neurological disorders such as spinal cord injury (SCI). | INS | $73.1M | 2013 | ||||||
Computer chips powered by living neurons | Synthetic biology to merge live biological neurons with silicon to create a new hybrid-biological computer chip. | $1M | 2011 | ||||||
Neuromodulation. Magnetic pulses to send those tones directly into the brain to create positive feedback on its own. | TMS | $250k | 2011 | ||||||
Brain Injury Monitor | $37.9M | 2010 | |||||||
Develops neurostimulation therapies for patients suffering with unmet medical needs. | $80.5M | 2008 | |||||||
Develop advanced applications and training technologies leading the way for neuroscience based interventions. | software technology that utilizes a 'measure-then-train' approach combining sensitive diagnostic metrics | 2007 | |||||||
NeuroNexus Technologies, Inc., a neuro-technology company, develops and commercializes neural interface technology, components, and systems for neuroscience and clinical applications. It offers neural probes and systems for single-unit, multi-unit, and local field potential electrophysiology; systems, instrumentation, and accessories to support electrophysiology experiments, including chronic drives, three-electrode experiment stands, and data streaming systems; electrode instrumentation; and computer-controlled insertion tools. | 2004 | ||||||||
Neuralynx, Inc. (Neuralynx) is an internationally recognized provider of electrophysiology data recording systems and solutions for neuroscience research, as well as for practical human medical data recording. Neuralynx specializes in the development of cutting-edge electrophysiology data recording systems and experiment accessories while providing quality, long term customer guidance and support. | electrophysiology data recording systems and solutions for neuroscience research | 1993 | |||||||
“Plexon is a pioneer and leading innovator of custom high performance solutions for data acquisition, behavioral research and advanced analysis specifically designed for neuroscience research. Our equipment and solutions lay the foundation for work performed around the globe in fields such as basic science, Brain-Machine Interfaces (BMI), neurodegenerative diseases, addictive behaviors and neuroprosthetics.” | BMI | 1983 | |||||||
“We are a team of neuroscientists, engineers, and clinicians that are taking an interdisciplinary approach to developing innovative neural interfaces to enable transformative basic neuroscience and translational approaches to effectively treat neurological disease. Using nanotechnology approaches, we create minimally invasive electrodes that are tailored to the specific anatomy of specific brain regions, including those deep inside the brain, for recording from and stimulating individual neurons and their immediate surroundings. With these electrodes, scientists and clinicians can unlock the mysteries of healthy brain function and directly modulate dysfunctional brain activity such as those found in patients suffering from Parkinson’s and epilepsy, locally, deep inside the brain, where is it is most effective.” | neural interfaces | 0 | |||||||
AI translator to ease animal-human communications within the decade | motion sensors that take the snapshot of your day to day activity | 0 | |||||||
Noninvasive neuromodulation with ultrasound | transcranial Focused Ultrasound Stimulation (tFUS) | 2024 | |||||||
steerable ultrasound arrays | Non-invasive | tFUS | SBIR grant to enhance sleep: https://www.sbir.gov/sbirsearch/detail/2192935 | $3.75M | 2019 | ||||
tFUS for deep brain stimulation | Non-invasive | tFUS | 2023 | ||||||
chair-mounted transcranial ultrasound | Non-invasive | tFUS | $18.3M | 2015 | |||||
transcranial ultrasound neuromodulation therapy for recovery from stroke | Non-invasive | tFUS | $24.4M | 2015 | |||||
The first product we’re developing is the S1 – a chip that can be used to detect muscle activity by reading the magnetic fields generated by muscle movement. We’re starting with muscle sensing because it’s a simpler, stronger set of signals to detect than that of brain activity, serving as an ideal stepping stone for building a brain sensor. Our goal with the S1 is to solve the limitations of a technique called surface electromyography, which is used for numerous muscle sensing applications despite suffering from the typical signal quality and usability challenges of electrical sensing techniques. The first application we’re focusing on is gesture control to unlock new forms of human-computer interaction for personal computing, augmented realities and gaming. The chip-scale form factor of the S1 means easy integration into wrist-wearables, smartwatches and rings for these applications. And the information advantage of this novel dataset could also lead to more advanced capabilities only possible with higher fidelity signals, additional degrees of freedom, ability to detect intention to move, and more. | Non-invasive | EMG | $11M | 2020 | |||||
First pea-sized brain stimulator designed for humans Precise brain stimulation with an implant that never touches the brain | Invasive | Neurostimulation | Miniature bioelectronics, under the skull but above the dura | 2022 | |||||
A new generation of portable, wearable medical imaging technology and therapeutic devices | Non-invasive | FNIRS | breakthroughs in novel lasers, opto-electronic and holographic system | $22M | 2016 | ||||
“Integrated neuro techology platform to understand, predict and act on data from any wearable, bio-sensor or EEG device.” | Non-invasive | EEGBio-sensor | Wearables | $800k | 2014 | ||||
“The Guardian Neuro-Intelligence Platform turns brain signals into actionable insights. Our platform is a closed-loop system which translates brain waves to actionable insights with the most intuitive neural interface to date.” | Non-invasive | Picks up brain signals from earbuds | $4.3M | 2017 | |||||
"Our reparative biotherapeutics are tailored for disease subtypes diagnosed by biomarkers, pathology and genetics. The biotherapeutics are delivered either by injection or locally by an implantable proprietary gene therapy device to facilitate the most efficient treatment of the disease.” | Invasive | ECB | encapsulated cell biodelivery (ECB) | $71k | 2000 |