Alzheimer’s Disease and Cognitive Aging
Women’s Health and Cognition
Investigator Initiated Clinical Trials
“Our overriding interest is in aging, cognition, and dementia both at the population level and at the level of individual adults. Our research agenda encompasses cognitive change that occurs as a usual concomitant of normal aging and more debilitating impairment that accompanies Alzheimer’s disease and other forms of dementia. Pathological processes that culminate in Alzheimer dementia are believed to begin years, if not decades, before the onset of mental symptoms. For this reason, we are interested in factors that affect cognitive skills at midlife, a time when therapeutic interventions offer the greatest potential of forestalling late-life impairment, as well at older ages, when cognitive impairment more typically first becomes apparent. One research theme pertains to adult women’s health. Here, we continue to examine cognitive consequences of estrogen, testosterone and other hormones, whose concentrations vary with age.”
Risk of dementia in patients with inflammatory bowel disease: a Danish population-based study. Alimentary pharmacology & therapeutics Sand, J. R., Troelsen, F. S., Horvath-Puho, E., Henderson, V. W., Sorensen, H. T., Erichsen, R. 2022
Rest-activity rhythms and cognitive impairment and dementia in older women: Results from the Women's Health Initiative. Journal of the American Geriatrics Society Xiao, Q., Shadyab, A. H., Rapp, S. R., Stone, K. L., Yaffe, K., Sampson, J. N., Chen, J., Hayden, K. M., Henderson, V. W., LaCroix, A. Z. 2022